This may sounds like a B-movie on the Sci-Fi Channel, but the CA-MRSA scare is all too real - one of several health alerts this year that proved just how vulnerable we are despite all our scientific know-how and advances in medicine. Bacteria, living organism made of one cell has mastered gene manipulation, enzyme technology, personal defence and technology transfer.

All invasive practical procedures, operations, plastic surgery, transplant surgery, hip or knee replacement, open heart surgery will soon come to a grinding halt. The very technology we’ve created to help us live more comfortable and, yes, often healthier lives will turn around and bite us-hard..........

  • Introduction
  • CA-MRSA
  • Cannula
  • Antibiotics
  • Pandamic

Introduction

Its not war, terrorist, credit crunch or the global warming that threaten our existence, but a antibiotic, antiseptic resistant bacteria are spreading all over the world with alarming rate. CDC noted, HA-MRSA & CA-MRSA is growing at an alarming rate now colonized in 53 million people worldwide.

Relatively a harmless bacteria that people carry in their nose and hands called as Staphylococcus has now suddenly becomes a dangerous predator, immune to antibiotics, chemical wash, antiseptic and antibacterial lotions.

Bacteria have a basic survival strategy: to colonize surfaces and grow as bio-films communities embedded in a gel-like polysaccharide matrix. These bacteria are now resistant to antiseptics, disinfectants, antibiotics and chemicals. They are not killed by phagocytes nor destroyed by immune system. 

The cell wall is complex and has various channels (efflux pump) to pump out chemicals we throw to kill them. 7-year study published in 2004 found that S. aureus is the 2nd most common infection of bloodstream infections in US hospitals and has become the 3rd most common cause of death.

MRSA Now Resists Last-Chance Antibiotic

New generation of bacteria is almost impossible to treat.

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CA-MRSA

Health authorities & politicians are continuing to treat MRSA as purely a hospital problem and trying to assuage public opinion. They are spending billions on a fighting a battle they will never win. CA-MRSA PVL Strain is a killer bug infecting healthy adults and children in one to two days.

Recently a new strain of MRSA has demonstrated resistance to the antibiotic Zyvox, which was considered to be the one solution that would work when all other antibiotics failed - until now. Although "isolated" cases of Zyvox-resistance have been reported in the past, in this case, 12 patients in the intensive care unit of a hospital in Madrid, Spain, all developed MRSA that failed to respond to the drug.

A major concern is that MRSA can be carried by asymptomatic patients. Worldwide, it is estimated that up to 53 million people are asymptomatic carriers of MRSA. One out of every five patients who develops an MRSA infection dies from it.

New generation of bacteria is almost impossible to treat become immune to powerful biocides (antiseptics and antibacterial solutions) as well as antibiotics. Doctors in India are now accepting they have a problem.....

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Cannula

Practical procedures like inserting urinary catheters, central venous catheters, blood tests and intra venous cannula create an entry point for bacteria to enter blood circulation. MRSA is said to be resistannt to antiseptics and disinfectants used to decontaminate skin before introducing needle and cannula through skin. IV cannula are the most frequently used device in the hospitals. One in 8 patient (70%-80%) entering hospital is treated via cannula.

Cannula manufacturers are still talking about "Needle-stick Injuries" as a major problem encountered in hospitals. The are aggressively marketing their so called "Safety cannula" despite published data prove the risk of contracting infection due to needle stick injury is considerably low. Between 1996-2004, in England, Wales & Northern Ireland, 9 Hepatitis C & 1 HIV infection in Health care workers was reported.

The number of people dying due MRSA, E Coli & C Diff in our hospitals has reached catastrophic proportion and infection is now the 3rd most common cause of death in the world. The evidence available clearly points to poor hygienic practice when staff perform practical procedures and is not associated with dirty hospitals, temporary staff or rapid turnover of patients ....

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Antibiotics

Antibiotics paved the way for doctors to develop new technologies (IVF, plastic surgery, hip replacement, minimally invasive surgery, stents, total parentral nutrition’s, transplant surgery and cardiac surgery).

There are currently considerable challenges with the treatment of infections caused by strains of clinically relevant bacteria that show multi-drug resistance. New antibiotic are urgently needed, but the bacteria have developed resistance to these new drugs. Linezolid Resistant Staphylococcus Aureus (LRSA):

Blaming antibiotic abuse now does not help, this should have been practiced since antibiotic was invented. Pharmaceutical companies R&D was stopped in 1970s, as this was not profitable enough to meet their obligation to shareholders. Wasted medical dollars

What the World Needs Now: Safe Non-Antibiotic Anti-Infectives

Media have been quick to report about new treatment, new cure and miracle cure for this problem. We are keeping constant watch and will report only treatment which helps. Its not so easy to develop an antibiotic but pharmaceutical companies are very keen to find a cure. Various companies marketing treatments "MRSA combatants", but non proved.

Pandemic

During influenza pandemic of 1918 more people died due to secondary Staphylococcus aureus than the World War I & II. The estimated potential worldwide death toll ranges from 7.4 million to 180 million to 360 million, extrapolating 1918’s deaths to today’s population. The Great Depression of 1930 resulted in illness with devastating effect and wiped out communities.

The WHO & the federal government fears that 9 million Americans may become sick as 2.5 million Americans are now colonized in USA. Research team analyzed 135 varieties of MRSA genes collected from 22 countries in Europe, Africa, Asia and the Americas.

Six Bacteria are among the biggest threats infectious diseases physicians (Medical profession) face today.

(1) Enterococcus faecium, (2) Staphylococcus aureus, (3) Klebsiella species, (4) Acinetobacter baumannii, (5) Pseudomonas aeruginosa, (6)Enterobacter species are now said to be resistant to most antibiotics and antiseptics.

To Wash or Not To Wash Hand

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